Interventi progettuali discreti in spazi museali. Utilizzo di tecnologie digitali per la fruizione di esperienze interattive naturali.

Il contributo propone una riflessione e una conseguente proposta di ricerca nell’ambito del design per la valorizzazione del patrimonio culturale attraverso l’utilizzo di tecnologie digitali. Tali strumenti, utili a creare narrazioni multilivello, catturare l’attenzione e coinvolgere i visitatori, talvolta si configurano come elementi che, per le loro caratteristiche tecniche, ostacolano la fruizione e la fluidità dell’interazione. Mediante la disamina dei campi di ricerca legati all’Ubiquitu...

Gestión de las interacciones durante una lección sobre la diferencial: una competencia del profesor de matemáticas

The Calcium Channel Blocker Gabapentin, a Benchmark Drug in Pain Studies, Inhibits Translocation of the Epsilon Isoform of Protein Kinase C in Cultured Nociceptors: A Novel Mechanism of Action

Gabapentin is a well-established anticonvulsant drug which is also effective for the treatment of neuropathic pain. Gabapentin, a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid, was originally developed in the early nineties as a third-generation antiepileptic drug. Although the exact mechanism leading to relief of allodynia and hyperalgesia caused by neuropathy is not known, the blocking effect of gabapentin on voltage-dependent calcium channels has been propo...

Cone-Like Functional Properties of cGMP-Gated Channels in Rod-Like Retinal Photoreceptors of Nocturnal Geckoes

Retinas of nocturnal geckoes only contain scotopic photoreceptors with rod-shaped outer segments and sensitivities to light similar to the one of retinal rods from other species of lower vertebrates. However, these cells are not rods, but ” originally derived from cones in cone-only retinas of ancestral diurnal geckoes as a consequence of evolutionary pressure that forced adaptation to nocturnal behavior. Several interesting adaptations of these rod-like cones have been studied to date; molec...